“On the other hand, berberine’s weight loss effects are thought to be mediated through different pathways, such as AMPK activation and improvements in insulin sensitivity,” Perks surmises.

“GLP-1 agonists mimic the action of a hormone called glucagon-like peptide-1 (GLP-1), which helps reduce food intake and appetite through the augmentation of insulin secretion, suppression of glucagon secretion, and deceleration of gastric emptying.” “While both berberine and GLP-1 agonists like Ozempic and Wegovy have some effects on weight, they work through different mechanisms,” explains Perks. While berberine is available over the counter, some practitioners prescribe it for weight loss, especially for those with insulin resistance, such as is the case with prediabetes and Type 2 diabetes.īerberine may have been dubbed ‘Nature’s Ozempic’ online due to its weight loss effects but the two are significantly different.

“It exhibits various biological activities and has been shown to have pharmacological effects such as dilating blood vessels, reducing blood pressure, regulating immunity, inducing penile erection, inhibiting inflammation, and treating cancer,” she explains. “While it does not have a comprehensive nutrient profile like vitamins or minerals, berberine has been studied for its potential benefits in managing blood sugar levels, improving insulin sensitivity, reducing obesity, supporting cardiovascular health, and reducing inflammation,” says registered nutritional therapist Helen Perks. It’s linked with many health benefits, including weight loss, and is usually available in supplement form.

Berberine is a naturally occurring compound found in plants like barberry, goldenseal, tree turmeric, and Oregon grape.

Blackjack energy pills side effects